Decarboxylative acylation of indolines with α-keto acids under palladium catalysis: a facile strategy for the synthesis of 7-substituted indoles.
نویسندگان
چکیده
Palladium-catalyzed decarboxylative acylation of highly substituted indolines with α-keto acids via C-H bond activation is described. This protocol provides efficient access to C7-carbonylated indoles known to have diverse biological profiles.
منابع مشابه
Palladium-catalyzed decarboxylative acylation of O-methyl ketoximes with α-keto acids.
A mild, practical and efficient palladium-catalyzed decarboxylative ortho-acylation of O-methyl ketoximes with α-keto acids via C-H bond activation is described. In these reactions, a broad range of O-methyl ketoximes and α-keto acids undergoes the decarboxylative cross-coupling reactions with high selectivities and good tolerance.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 91 شماره
صفحات -
تاریخ انتشار 2014